Collaboration and License Agreements - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended				9 Months Ended
	Feb. 28, 2023	Sep. 30, 2024	Mar. 31, 2024	Dec. 31, 2023	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue		$ 19,570			$ 43,735	$ 173,384	$ 87,165
Vertex
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Strategic collaboration agreement, term	4 years
Milestone payment			$ 75,000	$ 17,500
Stock issued	$ 19,400
Revenue		19,600			43,700	172,400	87,200
Vertex | Private Placement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Net proceeds from issuance of common stock	$ 26,300
Number of shares purchases in equity investment (in shares)	1,618,613
Consideration amount	$ 485,000
Vertex | License
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Up-front payment	223,700
Revenue, remaining performance obligation, amount	232,000	53,900		$ 142,800		53,900
Premium	$ 6,900
Vertex | Collaboration service revenue
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue		2,600			3,900	12,200	12,300
Vertex | Recognition of upfront and milestone payments
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue		$ 17,000			$ 39,800	$ 17,400	$ 74,900