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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid‑in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Beginning balances (in shares) at Dec. 31, 2022   31,394,767      
Beginning balances at Dec. 31, 2022 $ 212,554 $ 3 $ 402,893 $ (2,057) $ (188,285)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options (in shares)   18,344      
Issuance of common stock upon exercise of stock options 129   129    
Vesting of early exercised options (in shares)   10,153      
Vesting of early exercised options 26   26    
Vesting of restricted stock units (in shares)   91,859      
Issuance of common stock in connection with the Vertex Agreement (in shares)   1,618,613      
Issuance of common stock in connection with the Vertex Agreement 19,407   19,407    
Stock‑based compensation 2,755   2,755    
Other comprehensive income 1,415     1,415  
Net income (loss) (6,674)       (6,674)
Ending balances (in shares) at Mar. 31, 2023   33,133,736      
Ending balances at Mar. 31, 2023 229,612 $ 3 425,210 (642) (194,959)
Beginning balances (in shares) at Dec. 31, 2022   31,394,767      
Beginning balances at Dec. 31, 2022 $ 212,554 $ 3 402,893 (2,057) (188,285)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Vesting of early exercised options (in shares) 14,745        
Ending balances (in shares) at Dec. 31, 2023 33,437,296 33,437,296      
Ending balances at Dec. 31, 2023 $ 242,360 $ 3 437,132 195 (194,970)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options (in shares) 30,888 30,888      
Issuance of common stock upon exercise of stock options $ 206   206    
Vesting of early exercised options (in shares) 11,334 3,411      
Vesting of early exercised options $ 13   13    
Vesting of restricted stock units (in shares)   132,458      
Stock‑based compensation 3,733   3,733    
Other comprehensive income (441)     (441)  
Net income (loss) $ 23,496       23,496
Ending balances (in shares) at Mar. 31, 2024 33,604,053 33,604,053      
Ending balances at Mar. 31, 2024 $ 269,367 $ 3 $ 441,084 $ (246) $ (171,474)