Collaboration and License Agreements - Additional Information (Details) - USD ($) $ in Millions	1 Months Ended		12 Months Ended
	Oct. 31, 2023	Feb. 28, 2023	Dec. 31, 2023
Vertex
Commitments and Contingencies
Vertex agreement, term		4 years
Milestone payment	$ 17.5
Shares issued		$ 19.4
Cumulative catch-up adjustment		7.8
Vertex | Private Placement
Commitments and Contingencies
Net proceeds from issuance of common stock		$ 26.3
Number of shares purchases in equity investment (in shares)		1,618,613
Consideration amount		$ 485.0
Vertex | License
Commitments and Contingencies
Up-front payment		223.7
Revenue, remaining performance obligation, amount		232.0	$ 139.0
Premium		$ 6.9
Pierrepont Therapeutics, Inc
Commitments and Contingencies
Revenue recognized			$ 0.0