CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Cash flows from operating activities:
Net loss	$ (94,616)	$ (51,158)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation expense	1,895	1,117
Loss on disposal of property and equipment	0	74
Stock‑based compensation expense	9,895	2,526
Amortization of premiums and discounts on marketable securities, net	151	0
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(14,022)	(6,733)
Right-of-use assets, operating leases	7,651
Other non-current assets	(4,338)	(331)
Accounts payable	5,287	(715)
Accrued expenses and other current liabilities	1,762	3,962
Deferred rent	0	396
Operating lease liabilities	(7,451)
Net cash used in operating activities	(93,786)	(50,862)
Cash flows from investing activities:
Purchases of property and equipment	(2,887)	(4,580)
Purchases of marketable securities	(221,977)	0
Maturities of marketable securities	76,214	0
Net cash used in investing activities	(148,650)	(4,580)
Cash flows from financing activities:
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs	0	115,831
Proceeds from issuance of common stock upon initial public offering, net of issuance costs	0	190,691
Proceeds from exercise of stock options	195	410
Proceeds from the early exercise of stock options	0	529
Proceeds from issuance of common stock under the employee stock purchase plan	284	0
Net cash provided by financing activities	479	307,461
Net (decrease) increase in cash, cash equivalents and restricted cash	(241,957)	252,019
Cash, cash equivalents and restricted cash at beginning of year	291,064	39,045
Cash, cash equivalents and restricted cash at end of year	49,107	291,064
Supplemental cash flow disclosures:
Purchases of property and equipment included in accounts payable and accrued expenses	88	155
Conversion of preferred stock to common stock upon initial public offering	0	197,489
Vesting of options early exercised subject to repurchase	135	250
Recognition of right-of-use asset upon adoption of ASC 842	32,991
Transfer of deposits for equipment from operating to investing cash flows	$ 495	$ 0