Commitments and Contingencies - License Agreement (Details) $ in Thousands	12 Months Ended			13 Months Ended
	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2018 USD ($) installment item shares	Jun. 30, 2020 USD ($)
Commitments and Contingencies
Research and development expense	$ 35,926	$ 21,102
Expense relating to milestone obligation	0	0
License agreement with a third-party
Commitments and Contingencies
Upfront research fees			$ 400	$ 200
Number of installments | installment			2
Value of assets purchased (in shares) | shares			86,558
Value of assets purchased			$ 200
Potential milestone payment obligation			$ 2,600
Number of licensed products | item			3
Patent costs	100	$ 100
License agreement with a third-party | Maximum
Commitments and Contingencies
Annual license maintenance fee	$ 100