<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2020-07-28</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001679273</issuerCik>
        <issuerName>Lamb Weston Holdings, Inc.</issuerName>
        <issuerTradingSymbol>LW</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001688987</rptOwnerCik>
            <rptOwnerName>Carter Micheline C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O LAMB WESTON HOLDINGS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>599 S. RIVERSHORE LANE</rptOwnerStreet2>
            <rptOwnerCity>EAGLE</rptOwnerCity>
            <rptOwnerState>ID</rptOwnerState>
            <rptOwnerZipCode>83616</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Human Resources Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2020-07-28</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>F</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>4231</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>62.42</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>25617.03</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Withholding of shares of common stock to satisfy tax withholding obligations in connection with the vesting of restricted stock units and performance shares for which the applicable performance condition had been satisfied but remained subject to the reporting person's continued service through the vesting date.</footnote>
        <footnote id="F2">Since the date of the reporting person's last ownership report, she transferred 4,712 shares of Lamb Weston common stock to her ex-husband pursuant to a domestic relations order. The reporting person no longer reports as beneficially owned any securities owned by her ex-husband.  Amount also includes 206.02 additional shares acquired since the date of the reporting person's last report through a dividend reinvestment feature.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Eryk J. Spytek, as Attorney-in-Fact</signatureName>
        <signatureDate>2020-07-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
