X0306 4 2020-02-10 0 0001490978 Schrodinger, Inc. SDGR 0001686178 WRIGHT TIMOTHY MICHAEL C/O SCHRODINGER, INC., 120 WEST 45TH STREET, 17TH FLOOR NEW YORK NY 10036 1 0 0 0 Stock Option (right to buy) 17.00 2020-02-10 4 A 0 12909 0.00 A 2030-02-04 Common Stock 12909 12909 D The option was granted on February 5, 2020. The commencement of vesting was contingent upon the closing of the Issuer's initial public offering, which occurred on February 10, 2020. The shares underlying the option are scheduled to vest in full on February 5, 2021. /s/ Yvonne Tran, as attorney-in-fact for Timothy Michael Wright 2020-02-10