X0306 4 2023-01-03 0 0000872589 REGENERON PHARMACEUTICALS, INC. REGN 0001683607 Bassler Bonnie L 777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591 1 0 0 0 Common Stock 2023-01-03 4 A 0 165 0.0 A 1247 D Non-Qualified Stock Option (right to buy) 725.89 2023-01-03 4 A 0 1929 0.0 A 2033-01-03 Common Stock 1929 1929 D Reflects an acquisition of time-based vesting restricted stock units each representing a contingent right to receive one share of the Issuer's common stock. On the date of the Issuer's first annual meeting of shareholders following the date of grant, a portion of these stock options equal to the portion of one year that has passed from the date of grant shall then become exercisable, and the remainder shall become exercisable on the first anniversary of the date of grant. /s/**Bonnie L. Bassler 2023-01-05