CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Millions, $ in Millions	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Revenue:
Total revenue	$ 1,862	$ 6,066
Operating expenses:
Cost of sales	792	1,017
Research and development	1,131	554
Selling, general and administrative	305	268
Total operating expenses	2,228	1,839
(Loss) income from operations	(366)	4,227
Interest income	109	15
Other expense, net	(48)	(13)
(Loss) income before income taxes	(305)	4,229
(Benefit from) provision for income taxes	(384)	572
Net income	$ 79	$ 3,657
Earnings per share:
Basic (in usd per share)	$ 0.20	$ 9.09
Diluted (in usd per share)	$ 0.19	$ 8.58
Weighted average common shares used in calculation of earnings per share:
Basic (in shares)	386	402
Diluted (in shares)	405	426
Product sales
Revenue:
Total revenue	$ 1,828	$ 5,925
Other revenue
Revenue:
Total revenue	$ 34	$ 141