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Property, Plant and Equipment, Net (Tables)
3 Months Ended
Mar. 31, 2023
Property, Plant and Equipment [Abstract]  
Schedule of Property and Equipment, Net
Property, plant and equipment, net, as of March 31, 2023 and December 31, 2022 consisted of the following (in millions):
March 31,December 31,
20232022
Land$11 $11 
Manufacturing and laboratory equipment312 284 
Leasehold improvements
471 460 
Furniture, fixtures and other23 21 
Computer equipment and software
46 38 
Construction in progress
370 281 
Right-of-use asset, financing (Note 12)
1,521 1,581 
Total2,754 2,676 
Less: Accumulated depreciation
(736)(658)
Property and equipment, net
$2,018 $2,018