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Related Party Transactions - Narrative (Details) - USD ($)
1 Months Ended 12 Months Ended
Feb. 28, 2018
Feb. 15, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Related Party Transaction [Line Items]          
Accounts receivable     $ 337,000 $ 899,000  
Affiliated Entity | Covington          
Related Party Transaction [Line Items]          
Legal services     100,000 200,000 $ 200,000
Outstanding accounts payable balances     0 0  
Equity Method Investee | AstraZeneca          
Related Party Transaction [Line Items]          
Payments received     7,900,000 34,000,000 $ 1,100,000
Accounts receivable     $ 300,000 $ 900,000  
Series G Redeemable Convertible Preferred Stock          
Related Party Transaction [Line Items]          
Shares of stock issued (in shares) 55,666,004 55,666,004      
Price per share (usd per share) $ 10.06 $ 10.06      
Aggregate purchase price $ 560,000,000 $ 560,000,000