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Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2019
Accounting Policies [Abstract]  
Entities that Accounted for More than 10% of Total Revenue and Accounts Receivable
A significant portion of our revenue to date has been generated from the following entities that accounted for more than 10% of total revenue and accounts receivable for the periods presented:
 
Percentage of Revenue
Years Ended December 31,
 
Percentage of 
Accounts Receivable
December 31,
 
2019
 
2018
 
2017
 
2019
 
2018
Merck
61
%
 
49
%
 
31
%
 
13
%
 
30
%
BARDA
13
%
 
*

 
10
%
 
54
%
 
13
%
Vertex
10
%
 
*

 
*

 
17
%
 
22
%
AstraZeneca
*

 
34
%
 
15
%
 
*

 
*

Alexion
*

 
*

 
36
%
 
*

 
*

DARPA
*

 
*

 
*

 
*

 
16
%
Massachusetts Life Sciences Center
*

 
*

 
*

 
*

 
12
%
________
* - Represents an amount of less than 10%
Estimated Useful Lives of Property and Equipment
The estimated useful lives of property and equipment are described below:
 
 
Estimated Useful Life
Laboratory equipment
 
5 years
Leasehold improvements
 
Lesser of estimated useful life of improvement
or remaining life of related lease
Computer equipment and software
 
3 years
Other assets including automobiles, furniture and fixtures
 
5 years
Right of use asset, financing
 
Lease term
Property and equipment, net as of December 31, 2019 and 2018 consists of the following (in thousands):
 
 
December 31,
 
 
2019
 
2018
Building (1)
 
$

 
$
140,442

Laboratory equipment
 
108,257

 
96,907

Leasehold improvements (1)
 
152,426

 
13,741

Furniture, fixtures and other
 
3,316

 
2,122

Computer equipment and software
 
11,985

 
11,513

Internally developed software
 
7,020

 
7,020

Right-of-use asset, financing
 
9,853

 

Construction in progress
 
3,222

 
4,688

 
 
296,079

 
276,433

Less: Accumulated depreciation
 
(94,584
)
 
(64,456
)
Property and equipment, net
 
$
201,495

 
$
211,977


_________
(1) Leasehold improvements related to our Moderna Technology Center manufacturing facility were previously capitalized as building under ASC 840 and are now included in leasehold improvements under ASC 842 (Note 2). 
Components of Accumulated Other Comprehensive Loss
The components of accumulated other comprehensive gain (loss) for the years ended December 31, 2019 and 2018 are as follows (in thousands): 
 
Unrealized Gain (Loss) on Available-for-Sale Debt
Securities
Accumulated other comprehensive loss, balance at December 31, 2017
$
(1,157
)
Other comprehensive loss
(163
)
Accumulated other comprehensive loss, balance at December 31, 2018
(1,320
)
Other comprehensive income
3,124

Accumulated other comprehensive gain, balance at December 31, 2019
$
1,804

Effect of Adoption of ASC 606 on Condensed Financial Statements
The following tables summarize the effects of adopting ASC 606 on our consolidated financial statements at December 31, 2019, and for the year ended December 31, 2019 (in thousands, except per share data):
 
 
As of December 31, 2019
Consolidated Balance Sheet
 
As reported under ASC 606
 
Adjustments
 
Balance without adoption of ASC 606
Deferred revenue, current
 
$
63,310

 
$
(8,054
)
 
$
55,256

Deferred revenue, non-current
 
138,995

 
4,012

 
143,007

Accumulated deficit
 
(1,496,454
)
 
6,785

 
(1,489,669
)
 
 
Year Ended December 31, 2019
Consolidated Statement of Operations
 
As reported under ASC 606
 
Adjustments
 
Amount without adoption of ASC 606
Revenue:
 
 
 
 
 
 
   Collaboration revenue
 
$
42,803

 
$
2,767

 
$
45,570

   Collaboration revenue from related party
 
5,233

 
32,002

 
37,235

Total revenue
 
60,209

 
34,769

 
94,978

Loss from operations
 
(545,720
)
 
34,769

 
(510,951
)
Loss before income taxes
 
(514,716
)
 
34,769

 
(479,947
)
Net loss
 
(514,021
)
 
34,769

 
(479,252
)
Net loss per share - basic and diluted
 
(1.55
)
 
0.10

 
(1.45
)
The cumulative effect of applying both ASC 606 and ASC 842 on our consolidated balance sheets as of January 1, 2019 was as follows (in thousands):
 
 
Balance as of December 31, 2018 (1)
 
Effect of the Adoption of
 
Balance as of January 1, 2019
 
 
 
ASC 842
 
ASC 606
 
Assets:
 
 
Accounts receivable
 
$
11,686

 
$

 
$
(2,738
)
 
$
8,948

Prepaid expenses and other current assets
 
28,399

 
(300
)
 

 
28,099

Property and equipment, net
 
211,977

 
(2,483
)
 

 
209,494

Right-of-use assets, operating leases
 

 
63,334

 

 
63,334

Total assets
 
$
1,962,149

 
$
60,551

 
$
(2,738
)
 
$
2,019,962

Liabilities and Shareholders’ Equity:
 
 
 
 
 
 
 
 
Deferred revenue
 
$
109,056

 
$

 
$
(27,281
)
 
$
81,775

Other current liabilities
 
3,464

 
5,867

 

 
9,331

Deferred revenue, non-current
 
165,352

 

 
(3,441
)
 
161,911

Operating lease liabilities, non-current
 

 
64,250

 

 
64,250

Finance lease liabilities, non-current
 

 
37,718

 

 
37,718

Deferred lease obligation, non-current
 
10,006

 
(10,006
)
 

 

Lease financing obligation
 
33,489

 
(33,489
)
 

 

Accumulated deficit
 
(1,006,627
)
 
(3,789
)
 
27,984

 
(982,432
)
Total liabilities and shareholders’ equity
 
$
1,962,149

 
$
60,551

 
$
(2,738
)
 
$
2,019,962

_______
(1) As reported in our 2018 Annual Report on Form 10-K.
The following table summarizes our total consolidated net revenue from our strategic collaborators for the periods presented (in thousands):
 
 
Years Ended
Collaboration Revenue by Strategic Collaborator:
 
December 31, 2019
as reported
(under ASU 606)
 
December 31, 2019
without adoption of 606
(under ASC 605)
 
December 31, 2018
as reported
(under ASC 605)
Merck
 
$
36,608

 
$
38,977

 
$
66,082

AstraZeneca
 
5,233

 
37,235

 
45,993

Vertex
 
6,195

 
6,593

 
10,437

Total collaboration revenue
 
$
48,036

 
$
82,805

 
$
122,512

Reconciliation of Cash and Cash Equivalents
The following table provides a reconciliation of cash, cash equivalents and restricted cash in the consolidated balance sheets that sum to the total of the same such amounts shown in the consolidated statements of cash flows (in thousands):

 
 
As of December 31,
 
 
2019
 
2018
Cash and cash equivalents
 
$
235,876

 
$
658,364

Restricted cash
 
1,032

 
595

Restricted cash, non-current
 
10,791

 
11,532

Total cash, cash equivalents and restricted cash shown in the consolidated
    statements of cash flows
 
$
247,699

 
$
670,491