EX-FILING FEES

Exhibit 107

Calculation of Filing Fee Tables

S-8

(Form Type)

AVROBIO, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

Security Type

Security Class Title

Fee
Calculation
Rule

Amount
Registered⁽¹⁾

Proposed
Maximum
Offering
Price Per
Unit

Maximum
Aggregate
Offering
Price

Fee
Rate

Amount of
Registration
Fee

Equity

Common stock, par value $0.0001 per share

Rule 457(h)

1,747,853⁽²⁾

$1.42⁽³⁾

$2,481,951.26

.0000927

$230.08

Equity

Common stock, par value $0.0001 per share

Rule 457(c) and Rule 457(h)

436,963⁽⁴⁾

$1.21⁽⁵⁾

$528,725.23

.0000927

$49.02

Total Offering Amounts

$3,010,676.49

$279.10

Total Fee Offsets

—

Net Fee Due

$279.10

(1)

Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement shall also cover any additional shares of common stock which become issuable by reason of any stock dividend, stock split, recapitalization or any other similar transaction effected without the receipt of consideration which results in an increase in the number of the registrant’s outstanding shares of common stock.

(2)

Represents an automatic increase of 1,747,853 shares of common stock to the number of shares available for issuance under the Registrant’s 2018 Stock Option and Incentive Plan (the “Plan”), effective January 1, 2022. Shares available for issuance under the Plan were previously registered on a registration statement on Form S-8 filed with the Securities and Exchange Commission on June 21, 2018 (Registration No. 333-225788), March 25, 2019 (Registration No. 333-230494), March 16, 2020 (Registration No. 333-237203), August 6, 2020 (Registration No. 333-241400) and March 18, 2021 (Registration No. 333-254466).

(3)	Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act, and based on the average of the high and low sales prices of the registrant’s common stock, as quoted on the Nasdaq Global Select Market, on March 11, 2022.

(4)

Represents an automatic increase of 436,963 shares of common stock to the number of shares available for issuance under the registrant’s 2018 Employee Stock Purchase Plan (the “ESPP”), effective January 1, 2022. Shares available for issuance under the ESPP were previously registered on a registration statement on Form S-8 filed with the Securities and Exchange Commission on June 21, 2018 (Registration No. 333-225788), March 25, 2019 (Registration No. 333-230494), March 16, 2020 (Registration No. 333-237203) and March 18, 2021 (Registration No. 333-254466).

(5)

Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457 of the Securities Act, and based on 85% of $1.42 per share, which represents the average of the high and low prices of the registrant’s common stock reported on the Nasdaq Global Select Market on March 11, 2022. Pursuant to the ESPP, the purchase price of the shares of common stock reserved for issuance thereunder will be 85% of the fair market value of a share of common stock on the first trading day of the offering period or on the exercise date, whichever is less.