X0306 4 2021-06-10 0001681087 AVROBIO, Inc. AVRO 0001635046 Vickers Philip J. C/O AVROBIO, INC. ONE KENDALL SQUARE, BLDG. 300, SUITE 201 CAMBRIDGE MA 02139 1 Stock Option (Right to Buy) 9.63 2021-06-10 4 A 0 17438 0 A 2031-06-09 Common Stock 17438 17438 D The option shall vest in full upon the earlier of June 10, 2022 or the date of the Issuer's 2022 Annual Meeting of Stockholders, subject to the reporting person's continued service as a director through such vesting date. Exhibit 24 - Power of Attorney /s/ Christopher Gerry, Attorney in Fact for Philip J. Vickers 2021-06-14