X0306 4 2019-01-16 1 0001681087 AVROBIO, Inc. AVRO 0001717728 SVLSF VI, LLC ONE BOSTON PLACE, SUITE 3900 201 WASHINGTON STREET BOSTON MA 02108 0 0 1 0 0001642251 SV Life Sciences Fund VI, L.P. ONE BOSTON PLACE, SUITE 3900 201 WASHINGTON STREET BOSTON MA 02108 0 0 1 0 0001667605 SV Life Sciences Fund VI Strategic Partners, L.P. ONE BOSTON PLACE, SUITE 3900 201 WASHINGTON STREET BOSTON MA 02108 0 0 1 0 0001717730 SV Life Sciences Fund VI (GP), L.P. ONE BOSTON PLACE, SUITE 3900 201 WASHINGTON STREET BOSTON MA 02108 0 0 1 0 Common Stock 2019-01-16 4 J 0 778663 0.00 D 1866791 I See Footnote Common Stock 2019-01-16 4 J 0 26660 0.00 D 63913 I See Footnote SV Life Sciences Fund VI, L.P. ("SV Life LP") distributed the shares to its limited partners on a pro rata basis. The shares are held directly by SV Life LP. SV Life Sciences Fund VI (GP), L.P. ("SV Fund VI GP") is the general partner of SV Life LP. The general partner of SV Fund VI GP is SVLSF VI, LLC. Each of SV Fund VI GP and SVLSF VI, LLC disclaims beneficial ownership of the shares owned directly by SV Life LP, except to the extent of any pecuniary interest therein. SV Life Sciences Fund VI Strategic Partners, L.P. ("SV Life SP LP") distributed the shares to its limited partners on a pro rata basis. The shares are held directly by SV Life SP LP. SV Fund VI GP is the general partner of SV Life SP LP. The general partner of SV Fund VI GP is SVLSF VI, LLC. Each of SV Fund VI GP, and SVLSF VI, LLC disclaims beneficial ownership of the shares owned directly by SV Life SP LP, except to the extent of any pecuniary interest therein. SV Life Sciences Fund VI, L.P., By: SV Life Sciences Fund VI (GP), L.P., Its: sole General Partner, By: SVLSF VI, LLC, Its: sole General Partner, By: Brent M.Faduski, Officer, /s/ Brent M.Faduski 2019-01-18 SV Life Sciences Fund VI Strategic Partners, L.P., By: SV Life Sciences Fund VI (GP), L.P., Its: sole General Partner, By: SVLSF VI, LLC, Its: sole General Partner, By:Brent M. Faduski, Officer, /s/Brent M. Faduski 2019-01-18 SV Life Sciences Fund VI (GP), L.P., By: SVLSF VI, LLC, Its: sole General Partner, By: Brent M. Faduski, Officer, /s/ Brent M. Faduski 2019-01-18 SVLSF VI, LLC, By: Brent M. Faduski, Officer, /s/ Brent M. Faduski 2019-01-18