X0306 4 2020-08-07 0 0001604821 Natera, Inc. NTRA 0001680739 Baynes Roy D. C/O NATERA, INC 201 INDUSTRIAL ROAD, STE 410 SAN CARLOS CA 94070 1 0 0 0 Common Stock 2020-08-07 4 M 0 1300 24.42 A 1300 D Common Stock 2020-08-07 4 S 0 1300 53.4715 D 0 D Stock Option (right to buy) 24.42 2020-08-07 4 M 0 1300 0 D 2028-09-13 Common Stock 1300 15230 D The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $53.35 to $53.50 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The option shares vest over three years. A third of the option shares vested and became exercisable on July 25, 2019 with the remaining shares vesting in 2 equal annual installments thereafter. The initial option will become fully vested and exercisable in the event that the Company is subject to a change in control. /s/ Tami Chen, attorney-in-fact 2020-08-11