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Stock-based Compensation Expense (Tables)
6 Months Ended
Jun. 30, 2025
Summary of Stock Option Activity The following table summarizes the Company’s stock option activity during the six months ended June 30, 2025:

 

 

 

Number of
Shares

 

 

Weighted
Average
Exercise Price

 

 

Weighted
Average
Remaining
Contractual
Term
(in years)

 

 

Aggregate
Intrinsic
Value

 

Outstanding at December 31, 2024

 

 

9,354,699

 

 

$

7.46

 

 

 

8.03

 

 

$

5,353,463

 

Granted

 

 

3,603,573

 

 

 

4.54

 

 

 

 

 

 

 

Exercised

 

 

(55,396

)

 

 

3.21

 

 

 

 

 

 

 

Cancelled

 

 

(820,564

)

 

 

7.58

 

 

 

 

 

 

 

Outstanding at June 30, 2025

 

 

12,082,312

 

 

$

6.60

 

 

 

8.08

 

 

$

22,168,239

 

Exercisable at June 30, 2025

 

 

5,418,213

 

 

$

8.46

 

 

 

7.16

 

 

$

7,593,294

 

Weighted Average Assumptions Used to Calculate Fair Value of Stock Option

The fair value of stock options granted during the three and six months ended June 30, 2025 and 2024 has been calculated on the date of grant using the following weighted average assumptions:

 

 

 

Three Months
Ended
June 30, 2025

 

 

Three Months
Ended
June 30, 2024

 

 

Six Months
Ended
June 30, 2025

 

 

Six Months
Ended
June 30, 2024

 

Risk-free interest rate

 

 

4.0

%

 

 

4.3

%

 

 

4.4

%

 

 

4.1

%

Expected dividend yield

 

 

0.0

%

 

 

0.0

%

 

 

0.0

%

 

 

0.0

%

Expected term (years)

 

 

5.9

 

 

 

5.8

 

 

 

6.0

 

 

 

6.0

 

Expected stock price volatility

 

 

110.5

%

 

 

102.8

%

 

 

110.1

%

 

 

103.1

%

Summary of Stock-Based Compensation Expense Recognized

The total compensation cost recognized in the statements of operations and comprehensive loss associated with all stock-based compensation awards granted by the Company is as follows (in thousands):

 

 

 

Three Months Ended
June 30,

 

 

Six Months Ended
June 30,

 

 

 

2025

 

 

2024

 

 

2025

 

 

2024

 

General and administrative

 

$

2,320

 

 

$

2,681

 

 

$

4,503

 

 

$

5,268

 

Research and development

 

 

555

 

 

 

1,663

 

 

 

1,539

 

 

 

2,992

 

Total stock-based compensation expense

 

$

2,875

 

 

$

4,344

 

 

$

6,042

 

 

$

8,260

 

Grants Outside of 2016 Stock Incentive Plan and 2019 Stock Incentive Plan  
Summary of Restricted Stock Activity

The following table summarizes the Company’s restricted stock unit activity during the six months ended June 30, 2025:

 

 

 

Number of
Shares

 

 

Weighted
Average Grant
Date Fair
Value

 

Unvested at December 31, 2024

 

 

43,072

 

 

$

9.25

 

Granted

 

 

57,105

 

 

 

4.16

 

Vested

 

 

(19,505

)

 

 

9.50

 

Cancelled

 

 

(10,003

)

 

 

6.02

 

Unvested at June 30, 2025

 

 

70,669

 

 

$

5.53