Segment Information - Schedule of Reportable Segment Revenue, Operating Expenses, and Net Loss (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Revenue from Contract with Customer, Including Assessed Tax	$ 80,000	$ 2,805
Operating expenses:
Research and development	63,386	71,801
Operating Expenses	101,897	113,469
General and administrative	36,448	41,668
Restructuring expenses	2,063	0
Total operating expenses	101,897	113,469
Loss from operations	(21,897)	(110,664)
Other income, net	12,172	13,329
Net loss	(9,725)	(97,335)
Operating Segments [Member]
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Revenue from Contract with Customer, Including Assessed Tax	80,000	2,805
Operating expenses:
Operating Expenses	101,897	113,469
Employee compensation expenses (excluding stock-based compensation expenses)	15,347	16,978
Stock-based compensation expenses	4,653	3,776
General and administrative	36,448	41,668
Restructuring expenses	2,063	0
Total operating expenses	101,897	113,469
Loss from operations	(21,897)	(110,664)
Other income, net	12,172	13,329
Net loss	(9,725)	(97,335)
Operating Segments [Member] | Losmapimod
Operating expenses:
Operating Expenses	20,801	29,069
Total operating expenses	20,801	29,069
Operating Segments [Member] | Pre-Development Candidate Expenses
Operating expenses:
Operating Expenses	14,008	14,536
Total operating expenses	14,008	14,536
Operating Segments [Member] | Pociredir
Operating expenses:
Operating Expenses	8,577	7,442
Total operating expenses	$ 8,577	$ 7,442