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Income Taxes - Schedule of Reconciliation of U.S. Federal Statutory Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]    
Federal income tax at statutory rate 21.00% 21.00%
Permanent differences (0.90%) (0.04%)
Federal and state research and development credits 15.14% 1.47%
Federal orphan drug credits 77.47% 9.41%
State income tax, net of federal benefit 6.09% 5.92%
Stock compensation (incentive stock options) (6.23%) (0.68%)
Stock compensation cancellations (17.71%) (0.18%)
Officers' compensation (5.11%) (1.06%)
Impact of ownership change (1283.66%) 0.00%
Deferred rate change (6.78%) (0.02%)
Other 3.75% 0.11%
Change in valuation allowance 1196.94% (35.93%)
Effective income tax rate 0.00% 0.00%