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Collaboration and License Agreements - Additional Information (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jul. 31, 2020
GSK Agreement            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Specified clinical and regulatory milestones $ 5.0          
Specified clinical and regulatory milestones phase two clinical trial 2.5          
GSK Agreement | Maximum            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Specified clinical and regulatory milestones 37.5          
Specified sales milestone 60.0          
Camp4 Agreement            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Specified clinical and regulatory milestones 35.0          
Camp4 Agreement | Maximum            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Specified clinical and regulatory milestones $ 35.0          
Series B Convertible Preferred Stock | GSK Agreement            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Shares issued for asset acquisition 12,500,000          
Sanofi Agreement            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Revenues $ 80.0          
Upfront payment 80.0          
Development and regulatory milestone payments 975.0          
Increase Decrease in Research and Development Expenses 8.1          
MyoKardia Agreement            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Non refundable upfront payment received 10.0          
Deferred Revenue     $ 0.9      
Reimbursement Payment Recieved 7.7 $ 7.2        
Unbilled Accounts Receivable Related To Reimbursable Research And Development Cost 0.0 0.5        
Accounts and Financing Receivable, after Allowance for Credit Loss 0.0 0.0        
Upfront payment           $ 10.0
Payment for prepaid research funding 2.5 2.5       2.5
Prepaid research funding payment received         $ 2.5  
MyoKardia Agreement | Maximum            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Milestone payment for certain identified targets           298.5
Milestone payment for certain other identified targets           $ 150.0
MyoKardia Agreement | Clinical and Regulatory Milestones            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Aggregate amount receivable on achievement of milestone   2.5   $ 2.5    
Research Development And Sales Arrangement Aggregate Amount Receivable Upon Achievement Of Milestone   2.5   $ 2.5    
Collaborative Arrangement            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Revenues 0.0 2.8        
Deferred Revenue $ 0.0 $ 0.0