STOCK-BASED COMPENSATION (Tables)

3 Months Ended

Mar. 31, 2025

Share-Based Payment Arrangement [Abstract]

Schedule of stock option activity

The following table presents the outstanding stock option activity:

	Number of Options		Weighted Average Exercise Price Per Share		Weighted Average Remaining Contractual Term (years)
Three months ended March 31, 2025:
Outstanding as of December 31, 2024:	147,616		$	27.13	9.5
Granted	28,057		3.09		9.8
Exercised	—		—		—
Forfeited	(2)		1,965.36		—
Expired	—		—		—
Outstanding as of March 31, 2025	175,671	(1)	23.27		9.3
Exercisable as of March 31, 2025	54,911		66.86		9.0

(1) Includes options related to 603 shares that are inducement awards and not granted under the 2018 Plan.

Schedule of fair value of options granted, assumptions

The weighted average grant date fair value of options granted during the three months ended March 31, 2025 was $3.08 per share based on the following assumptions used in the Black-Scholes option pricing model:

Expected volatility	162	%
Expected dividend yield	—	%
Expected term (in years)	10
Risk-free interest rate	4.67	%

Schedule of stock-based compensation expense

The stock-based compensation expense was recorded as follows (in thousands):

	Three Months Ended March 31,
	2025		2024
Research and development	$	3	$	4
Selling, general and administrative	88		81
Total stock-based compensation expense	$	91	$	85