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STOCK-BASED COMPENSATION (Tables)
 12 Months Ended
Dec. 31, 2023
Share-Based Payment Arrangement [Abstract]  
Schedule of fair value of options granted
Fair value of options granted is determined using the Black-Scholes option-pricing model with the following weighted average assumptions:
20232022
Risk-free interest rate5.3 %3.7 %
Expected dividend yield— %— %
Expected volatility128 %90.5 %
Expected term (in years)5.03.3
Schedule of stock option activity
The stock option activity consists of the following:
Number of
Options 		Weighted
Average
Exercise
Price Per
Share		Weighted
Average
Remaining
Contractual
Term
(years)
Aggregate
Intrinsic
Value (1)
Outstanding as of December 31, 20214,533$2,071.20 3.9$— 
Granted20,16369.48 5.0— 
Exercised—— —— 
Forfeited(1,278)— —— 
Expired(16)— —— 
Outstanding as of December 31, 202223,402204.00 3.9— 
Granted16,61615.00 5.0— 
Exercised—— —— 
Forfeited(3,282)— —— 
Expired(28)— —— 
Outstanding as of December 31, 202336,708119.70 4.0— 
Exercisable as of December 31, 202320,634
(2)
154.31 3.8— 
(1)
Calculated based on the difference between the estimated fair value of our stock and the exercise price of the underlying option. The estimated stock values used in the calculation was $15.00 and $71.52 per share for the years ended December 31, 2023 and 2022, respectively.
(2)
Includes options related to 8,249 shares that are inducement awards and not granted under the 2018 Plan.
Schedule of restricted stock unit activity
The restricted stock unit activity consists of the following:
Number of
Units		Weighted Average
Grant Date Fair Value Per Unit
Outstanding as of December 31, 20212$432.00 
Granted1,58734.44 
Vested(23)212.04 
Forfeited—— 
Outstanding as of December 31, 20221,56632.52 
Granted—— 
Vested(1,566)32.52 
Forfeited—— 
Outstanding as of December 31, 2023—— 
Schedule of stock-based compensation expense
The stock-based compensation expense was recorded as following (in thousands):
Years Ended December 31,
20232022
Research and development$17 $3 
General and administrative538 
(1)
708 
Total stock-based compensation expense$555 $711 
(1)
Includes $100,000 related to stock issued in exchange for marketing services.