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Common Stock Warrants and Common Stock Warrant Liability (Details Narrative) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 13, 2018
Aug. 31, 2018
Aug. 13, 2018
Jul. 24, 2018
Jun. 20, 2018
Nov. 21, 2017
Jun. 30, 2018
Nov. 30, 2017
Sep. 30, 2018
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Jun. 30, 2015
Warrants exercised                   (1,475,659)      
Common Stock Offering Warrants Issued                      
Share price (in dollars per share)                 $ 0.69 $ 0.69   $ 0.72  
Fair value adjustment of warrants                 $ 1 $ 1      
Proceeds from warrant exercises                   2,213      
Stock compensation expense                   $ 3,090 $ 2,818    
Number of share issued in transaction                   1,475,659      
Deemed dividend                   $ 333    
Unexercised warrants                   $ 3,181,841      
Common Stock Warrants Issued To Participants in Offering of the Company's Common Stock [Member]                          
Common Stock Offering Warrants Issued         1,133,909                
Number of shares purchased         1,133,909 4,657,500     1,133,909 1,133,909      
Exercise price (in dollars per share)         $ 1.50 $ 1.50     $ 1.82 $ 1.82      
Warrant term           5 years              
Description of method used           Lattice model              
Share price (in dollars per share)           $ 1.00     2.11 2.11      
Fair value of common stock warrant           $ 661              
Expected volatility rate           73.80% 72.60%            
Expected term           5 years 5 years            
Expected dividend rate           0.00% 0.00%            
Risk free interest rate           1.87% 2.80%            
Proceeds from warrant exercises         $ 1,700   $ 1,700            
Stock compensation expense             1,700            
Common Stock Warrant Issued to Underwriter of Common Stock Offering [Member]                          
Number of shares purchased               945,000          
Exercise price (in dollars per share)     $ 0.95 $ 1.47       $ 1.50          
Warrant term               5 years          
Description of method used               Lattice model          
Share price (in dollars per share)     $ 1.02 $ 1.38       $ 1.00          
Fair value of common stock warrant               $ 134          
Expected volatility rate     74.00% 72.40%       73.80%          
Expected term     4 years 3 months 4 years 3 months 29 days       5 years          
Expected dividend rate     0.00% 0.00%       0.00%          
Risk free interest rate     2.75% 2.83%       1.87%          
University of Arizona Common Stock Warrant [Member]                          
Number of shares purchased                         15,000
Exercise price (in dollars per share)                 $ 7.91 $ 7.91     $ 7.50
Warrant term                   5 years      
Description of method used                   Monte Carlo option pricing model      
Expected volatility rate                   77.70%      
Expected dividend rate                   0.00%      
Risk free interest rate                   1.93%      
Derivative liability                 $ 0 $ 0     $ 53
New Warrants November 8, 2017 [Member]                          
Number of shares purchased         1,133,909       341,750 341,750      
Exercise price (in dollars per share)         $ 1.82                
Proceeds from warrant exercises             $ 513            
Right Offering [Member]                          
Common Stock Offering Warrants Issued     5,357,052                    
Exercise price (in dollars per share)   $ 1.15 $ 1.15                    
Share price (in dollars per share)     $ 0.94                    
Fair value of common stock warrant     $ 3,600                    
Expected volatility rate 159.00%                        
Expected term 5 years                        
Expected dividend rate 0.00%                        
Risk free interest rate 2.77%                        
Number of share issued in transaction     5,357,052                    
Right Offering [Member] | Common Stock Purchase Warrants [Member] | Maxim Partners LLC [Member]                          
Common Stock Offering Warrants Issued   267,853 267,853                    
Exercise price (in dollars per share)   $ 1.725 $ 1.725                    
Share price (in dollars per share)     $ 0.94                    
Fair value of common stock warrant     $ 70                    
Expected volatility rate     159.00%                    
Expected term     5 years                    
Expected dividend rate     0.00%                    
Risk free interest rate     2.77%                    
Second Public Offering [Member]                          
Number of shares purchased           5,860,000              
Exercise price (in dollars per share)           $ 1.00