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Notes Payable, Related Parties (Details Narrative) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 25 Months Ended
Apr. 07, 2016
Sep. 30, 2016
Mar. 31, 2016
Apr. 30, 2013
Jun. 30, 2017
Jun. 30, 2017
Dec. 31, 2016
Dec. 31, 2015
Aug. 31, 2017
May 31, 2016
Aug. 31, 2015
Oct. 31, 2011
Settlement of outstanding obligations       $ 40                
Due to Employees       $ 72                
Interest expense related party         $ 0 $ 1 $ 55 $ 437        
Debt interest expense             32 418        
Interest expense on notes payable related parties             30 462        
Salary Obligation [Member]                        
Debt interest rate       4.25%                
Debt instrument payment       $ 1                
Debt instrument maturity date       Jun. 30, 2018                
Unsecured promissory note [Member]                        
Debt interest rate     12.00%                  
Settlement of outstanding obligations     $ 25                  
Outstanding debt including accrued interest               380   $ 389    
Amount of restated promissory note including accrued interest     $ 414                  
Description of debt payment    

The Revised Note of $414 requires the Company to pay an initial payment of $25 upon the effective date of the note, and monthly and quarterly payments of $10 and $25, respectively, thereafter, with interest accruing at 12% per annum. Additionally, the Revised Note provides for an acceleration of the amount due in the event of (i) a merger, sale or acquisition of substantially of the Company’s assets; (ii) initial public offering; (iii) total equity raise of $2.5 million or more; and (iii) debt financing of $2.5 million with an unaffiliated lender within thirty days of such events.

                 
Debt financing     $ 2,500                  
4.25% and 8% unsecured promissory note [Member]                        
Debt instrument payment       $ 1                
Debt instrument maturity date       May 30, 2018                
Outstanding debt including accrued interest             $ 73 $ 36        
Unsecured Promissory Note [Member]                        
Debt interest rate       8.00%                
4% unsecured promissory note [Member] | Chief executive officer [Member]                        
Description of debt payment              

The notes accrued interest at 4% per annum and matured in December 2015. The funds were used to meet working capital requirements. The Company repaid $35 on the promissory notes during 2015 and repaid the balance in May 2016.

       
Face amount debt               $ 195       $ 30
4% unsecured promissory note [Member] | Chief research officer [Member]                        
Face amount debt                       $ 30
6% unsecured promissory note [Member]                        
Face amount debt $ 27                      
Issuance of common stock settlment of debt 54,000                      
6% unsecured promissory note [Member] | advisory board [Member]                        
Description of debt payment                

The note accrued interest at 6% per annum and was due in February 2016. Upon maturity, the holder transferred the note to a certain stockholder who acquired the note. The maturity date of the note was then extended for ninety days. On April 7, 2016, this note was settled with the issuance of 54,000 shares of common stock.

     
Face amount debt                     $ 27  
Issuance of common stock settlment of debt                 54,000      
Equity Participation Promissory Notes [Member]                        
Debt interest rate   1.25%                    
Debt instrument payment   $ 14                    
Description of debt payment  

Interest continues to accrue on unpaid balances at 1.25% per month with the total outstanding balance to be paid in full by the earlier of (i) May 25, 2017, (ii) the sale, merger or acquisition of the Company or substantially all of its assets, or (iii) 45 days after an initial public offering. This settlement was fully paid at December 31, 2016.

                   
Face amount debt   $ 464                    
Debt interest expense   $ 88