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Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2017
Accounting Policies [Abstract]  
Schedule of employee stock-based compensation expense

The stock-based compensation expense recorded for the three and six months ended June 30, 2017 and 2016 is as follows:

 

    Three Months Ended June 30,   Six Months Ended June 30,  
    2017   2016   2017   2016  
                           
Research and development   $ 90   $ 87   $ 184   $ 174  
General and administrative   721   255     1,688     1,299  
Total stock-based compensation expense   $ 811   $ 342   $ 1,872   $ 1,473  
Schedule of outstanding potentially dilutive securities calculation of diluted loss per share attributable to common stockholders

The following table sets forth the outstanding potentially dilutive securities that have been excluded in the calculation of diluted loss per share attributable to common stockholders (in common stock equivalent shares):

 

    June 30,  
    2017     2016  
Series A convertible preferred stock           400,000  
Series B convertible preferred stock           454,581  
Convertible promissory notes           533,031  
Common stock purchase warrants     829,285       710,487  
Restricted stock units     386,649        
Common stock options     1,603,800       1,556,867  
Total     2,819,734       3,654,966