Common Stock Warrants and Common Stock Warrant Liability (Details) - Schedule of common stock warrant activity - shares		12 Months Ended
		Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Class of Warrant or Right [Line Items]
Outstanding at beginning			2,582,697	489,176
Outstanding at ending		4,531,447
Various [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Various
Term Date				Various-2020/2021
Exercise Price				Various
Outstanding at beginning				17,059
Issued
Exercised			(9,375)
Expired			(7,684)
Outstanding at ending
Common Stock Offering Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Common Stock Offering Warrants
Term Date				November 21, 2022
Exercise Price	[1]			$1.3659
Outstanding at beginning			143,501	143,501
Issued
Exercised		(21,787)
Expired
Outstanding at ending		121,714
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				November 21, 2022
Exercise Price				$30.00
Outstanding at beginning				47,250
Issued
Exercised			(47,250)
Expired
Outstanding at ending
Warrant Reissue [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Warrant Reissue
Term Date				December 20, 2023
Exercise Price				$36.40
Outstanding at beginning			56,696	56,696
Issued
Exercised
Expired
Outstanding at ending		56,696
Rights Offering Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Rights Offering Warrants
Term Date				July 25, 2023
Exercise Price				$23.00
Outstanding at beginning			202,943	202,943
Issued
Exercised		(499)
Expired
Outstanding at ending		202,444
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				August 13, 2023
Exercise Price				$34.50
Outstanding at beginning			13,393	13,393
Issued
Exercised
Expired
Outstanding at ending		13,393
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				July 11, 2024
Exercise Price				$33.75
Outstanding at beginning			8,334	8,334
Issued
Exercised
Expired
Outstanding at ending		8,334
Registered Direct Offering [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Registered Direct Offering
Term Date				July 28, 2025
Exercise Price				$9.00
Outstanding at beginning			177,500
Issued			177,500
Exercised
Expired
Outstanding at ending		177,500
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				July 28, 2025
Exercise Price				$10.00
Outstanding at beginning			13,315
Issued			13,315
Exercised
Expired
Outstanding at ending		13,315
Registered Direct Offering [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Registered Direct Offering
Term Date				September 8, 2025
Exercise Price				$2.88
Outstanding at beginning
Issued			176,372
Exercised			(176,372)
Expired
Outstanding at ending
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				March 4, 2025
Exercise Price				$3.76
Outstanding at beginning			13,228
Issued			13,228
Exercised
Expired
Outstanding at ending		13,228
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				April 21, 2025
Exercise Price				$3.97
Outstanding at beginning			118,073
Issued			118,073
Exercised
Expired
Outstanding at ending		118,073
Registered Direct Offering [Member[
Class of Warrant or Right [Line Items]
Warrant Type				Registered Direct Offering
Term Date				April 24, 2025
Exercise Price				$3.05
Outstanding at beginning			50,000
Issued			1,574,308
Exercised			(1,524,308)
Expired
Outstanding at ending		50,000
Private Warrant Inducement [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Private Warrant Inducement
Term Date				April 27, 2026
Exercise Price				$1.73
Outstanding at beginning			1,700,680
Issued			1,700,680
Exercised		(700,680)
Expired
Outstanding at ending		1,000,000
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				April 27, 2026
Exercise Price				$2.16
Outstanding at beginning			85,034
Issued			85,034
Exercised
Expired
Outstanding at ending		85,034
Private Placement Agreement [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Private Placement Agreement
Term Date				August 2, 2026
Exercise Price				$2.216
Outstanding at beginning
Issued		2,194,427
Exercised
Expired
Outstanding at ending		2,194,427
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				August 2, 2026
Exercise Price				$2.848
Outstanding at beginning
Issued		329,164
Exercised
Expired
Outstanding at ending		329,164
Dealer Manager Warrants [Member]
Class of Warrant or Right [Line Items]
Warrant Type				Dealer Manager Warrants
Term Date				March 23, 2026
Exercise Price				$2.50
Outstanding at beginning
Issued		148,125
Exercised
Expired
Outstanding at ending		148,125

[1] The initial exercise price of these warrants was $30.00 per share. Pursuant to antidilution price adjustment protection contained within these warrants, the initial exercise price of these warrants was adjusted downward to $29.40 on July 24, 2018, the record date of the Right’s Offering and downward to $19.00 per share on August 13, 2018. These warrants were further adjusted downward from $19.00 to $7.13 and to $2.1122 on January 28, 2020 and March 4, 2020, respectively, in connection with separate Registered Direct Offerings. These warrants were further adjusted downward from $2.1122 to $1.3659 on October 26, 2020 in connection with a Registered Direct Offering. These warrants are subject to further adjustment pursuant to antidilution price adjustment protection.