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Common Stock Warrants and Common Stock Warrant Liability (Details) - $ / shares
9 Months Ended 12 Months Ended
Sep. 30, 2019
Dec. 31, 2018
Dec. 31, 2017
Outstanding at beginning 561,343 321,590 41,465
Warrants issued 8,334  
Warrants Exercised (64,901) (73,783)  
Warrants Exercised (15,600)    
Expired Warrants 489,176 (24,406)  
Date Issued 2019-07    
Date Issued 2018-08    
Date issued 2018-08    
Term 5 years    
Excercise price (in dollars per share) $ 33.75    
Exercise Price (in dollars per share) 23.00    
Exercise Price (in dollars per share) $ 1.6875    
Outstanding at ending 489,176 561,343 321,590
Common Stock Offering - Dealer Manager Warrants [Member]      
Warrants issued   13,393  
Date Issued   2018-08  
Term   5 years  
Exercise Price (in dollars per share)   $ 34.50  
Common Stock Offering Warrants Issued [Member]      
Warrants issued   267,853 232,875
Date Issued   2018-08 2017-11
Term   5 years 5 years
Exercise Price (in dollars per share) [1]   $ 23.00 $ 30.00
Warrants issued [Member]      
Warrants issued   56,696  
Date Issued   2018-06  
Term   5 years  
Exercise Price (in dollars per share)   $ 36.40  
Common Stock Offering Underwriter Warrants [Member]      
Warrants issued     47,250
Date Issued     2017-11
Term     5 years
Exercise Price (in dollars per share)     $ 30.00
[1] The Common Stock warrants issued in November 2017 with an initial exercise price of $30.00 per share adjusted downward to $19.00 per share effective July 24, 2018 in connection with our Rights Offering, and may be subject to further downward adjustments, pursuant to antidilution price adjustment protection contained within those warrants.