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Organization and Description of Business (Details Narrative)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Feb. 06, 2020
Feb. 04, 2020
Aug. 13, 2018
$ / shares
shares
Jul. 16, 2019
USD ($)
$ / shares
shares
Nov. 21, 2017
$ / shares
shares
Dec. 31, 2019
USD ($)
Number
shares
Dec. 31, 2018
USD ($)
shares
Jan. 28, 2020
$ / shares
Aug. 31, 2018
$ / shares
shares
Jun. 30, 2018
$ / shares
shares
Nov. 30, 2017
$ / shares
shares
Dec. 08, 2016
$ / shares
shares
Organization and Description of Business (Textual)                        
Proceeds from issuance and sale of common stock, preferred stock, warrants exercise, convertible and other promissory notes | $           $ 67,200            
Proceeds from licensing fees | $           1,700            
Proceeds from product sales | $       $ 3,600   600            
Accumulated deficit | $           (95,867) $ (85,838)          
Cash, cash equivalents and short-term investments | $           $ 1,900            
Common Stock Offering Warrants Issued | shares                    
Issuance of common stock upon exercise of warrants | $           $ 1,788 $ 2,214          
Sales Revenue, Net [Member]                        
Organization and Description of Business (Textual)                        
Number of customers | Number           2            
Sales Revenue, Net [Member] | Customer one [Member]                        
Organization and Description of Business (Textual)                        
Percentage           12.00%            
Customer Revenues | $           $ 17            
Sales Revenue, Net [Member] | Customer Two [Member]                        
Organization and Description of Business (Textual)                        
Percentage           20.00%            
Customer Revenues | $           $ 28            
Accounts Receivable [Member] | Customer one [Member]                        
Organization and Description of Business (Textual)                        
Percentage           83.00%            
Customer Revenues | $           $ 123            
Public Offering [Member]                        
Organization and Description of Business (Textual)                        
Number of shares issued | shares       151,838 293,000             93,750
Unit price (in dollars per unit)         $ 20.00              
Adjusted downward common stock         $ 19.00              
Public Offering [Member] | Chief Executive Officer [Member]                        
Organization and Description of Business (Textual)                        
Number of shares issued | shares       34,815                
Public Offering [Member] | Employee [Member]                        
Organization and Description of Business (Textual)                        
Number of shares issued | shares       371                
Unit price (in dollars per unit)       $ 27.00                
Public Offering [Member] | Warrant [Member]                        
Organization and Description of Business (Textual)                        
Number of shares issued | shares       8,334 232,875             9,375
Exercise price (in dollars per share)       $ 33.75 $ 30.00             $ 192.00
Public Offering [Member] | Warrant [Member] | Roth Capital Partners [Member]                        
Organization and Description of Business (Textual)                        
Number of shares issued | shares         47,250              
Exercise price (in dollars per share)         $ 30.00              
Private Placement [Member] | Warrant [Member]                        
Organization and Description of Business (Textual)                        
Number of shares issued | shares                   56,696 56,696  
Exercise price (in dollars per share)                   $ 36.40 $ 30.00  
Rights Offering [Member]                        
Organization and Description of Business (Textual)                        
Exercise price (in dollars per share)     $ 23.00           $ 23.00      
Unit price (in dollars per unit)                 $ 23.00      
Number of subscriptions shares accept | shares                 267,853      
Common Stock Offering Warrants Issued | shares     267,853                  
Rights Offering [Member] | Warrant [Member]                        
Organization and Description of Business (Textual)                        
Number of shares issued | shares                 13,393      
Exercise price (in dollars per share)                 $ 34.50      
Subsequent Event [Member]                        
Organization and Description of Business (Textual)                        
Unit price (in dollars per unit)               $ 8.00        
Reverse split, description The Company issued 24 shares of Common stock to shareholders of record in connection with fractional shares as a result of a 1-for-20 reverse stock split of our outstanding common stock on February 4, 2020. 1-for-20 reverse split                    
Subsequent Event [Member] | Warrant [Member]                        
Organization and Description of Business (Textual)                        
Exercise price (in dollars per share)               $ 9.00