STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
Cash flows from operations:
Net loss	$ (48,809)	$ (75,410)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation	6,995	9,546
Depreciation	3,688	3,829
Non-cash operating lease expense	506	428
Impairment loss of fixed assets	81	222
Non-cash license revenue	(1,000)	0
Net amortization of investments	(453)	(2,151)
Gain on lease modification	(105)	0
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	1,818	6,367
Other assets	79	90
Accounts payable	(318)	832
Accrued expenses and other current liabilities	(1,442)	(3,368)
Non-current operating lease liabilities	(922)	(900)
Net cash used in operating activities	(39,882)	(60,515)
Sales and maturities of investments
Sales and maturities of investments	35,600	85,100
Purchases of investments	(43,416)	(93,552)
Purchase of property and equipment	(71)	(59)
Net cash used in investing activities	(7,887)	(8,511)
Proceeds from sale of common stock, pre-funded warrants and common stock warrants, net of offering costs
Proceeds from sale of common stock, pre-funded warrants and common stock warrants, net of offering costs	44,475
Proceeds from sale of common stock, pre-funded warrants and common stock warrants, net of offering costs		(17)
Proceeds from the exercise of common stock warrants	139	0
Proceeds from the exercises of stock options and purchases pursuant to employee stock purchase plan	25	1,255
Taxes paid related to net share settlement of equity awards	(65)	(451)
Net cash provided by financing activities	44,574	787
Decrease in cash and cash equivalents	(3,195)	(68,239)
Cash and cash equivalents, beginning of period	57,387	125,626
Cash and cash equivalents, end of period	$ 54,192	$ 57,387