144 0001779978 XXXXXXXX LIVE 0001679363 Morphic Holdings Inc. 001-38940 35 GATEHOUSE DRIVE, A2 WALTHAM MA 02451 7819960955 Praveen R. Tipirneni Officer Common J.P. Morgan Securities LLC

390 Madison Avenue 6th Floor New York NY 10017

64746 3561030 50093588 07/08/2024 Nasdaq Common 07/08/2024 Stock Option Exercise Issuer N 64746 07/08/2024 Cash Y The sales under this filing are from Cashless Option Exercises that will occur within 3 months from the date of this filing. 07/08/2024 12/27/2023 /s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Praveen R. Tipirneni