X0407 4 2023-06-28 0 0001679363 Morphic Holding, Inc. MORF 0001575843 Nashat Amir C/O POLARIS PARTNERS ONE MARINA PARK DRIVE, 8TH FL. BOSTON MA 02210 1 0 0 0 0 Common Stock 2023-06-28 4 J 0 93462 0.00 D 1860498 I By Polaris Partners VII, L.P. Common Stock 2023-06-28 4 J 0 935 0.00 A 935 I By Polaris Management Co. VII L.L.C. Common Stock 2023-06-28 4 J 0 935 0.00 D 0 I By Polaris Management Co. VII L.L.C. Common Stock 2023-06-28 4 J 0 145 0.00 A 145 D Common Stock 2023-06-28 4 J 0 6538 0.00 D 130153 I By Polaris Entrepreneurs' Fund VII, L.P. Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Polaris Partners VII, L.P. ("PP VII") to its partners. The shares are owned directly by PP VII. Polaris Management Co. VII, L.L.C. ("PMC VII") is the general partner of PP VII. The Reporting Person, a member of the Issuer's Board of Directors, is a member of PMC VII. Each of the Reporting Person, David Barrett ("Barrett"), Brian Chee ("Chee"), and Bryce Youngren ("Youngren" and, together with the Reporting Person, Barrett, and Chee, the "Managing Members") are the managing members of PMC VII. Each of the Managing Members, in their respective capacities with respect to PMC VII, may be deemed to have shared voting and dispositive power over the shares held by PP VII. Each of PMC VII and the Managing Members disclaims beneficial ownership of these securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. Represents a change in the form of ownership of PMC VII by virtue of the receipt of shares in the pro-rata in-kind distribution of common stock of the Issuer for no consideration by PP VII. The shares are owned by PMC VII. Each of the Managing Members, in their respective capacities with respect to PMC VII, may be deemed to have shared voting and dispositive power over the shares held by PMC VII. The Managing Members disclaim beneficial ownership of these securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by PMC VII to its interest holders. Represents a change in the form of ownership of the Reporting Person by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by PMC VII. Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Polaris Entrepreneurs' Fund VII, L.P. ("PEF VII") to its partners. The shares are owned directly by PEF VII. PMC VII is the general partner of PEF VII. Each of the Managing Members, in their respective capacities with respect to PMC VII, may be deemed to have shared voting and dispositive power over the shares held by PEF VII. Each of PMC VII and the Managing Members disclaims beneficial ownership of these securities and this report shall not be deemed an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. /s/ Lauren Crockett, Attorney-in-Fact for Amir Nashat 2023-06-30