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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss and comprehensive loss $ (21,239) $ (61,660)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation 9,706 11,262
Depreciation 335 321
Non-cash interest expense 568 601
Amortization of operating lease right-of-use assets 460 403
Changes in operating assets and liabilities:    
Accounts receivable (6,352) (7,038)
Inventories (13,343) (1,561)
Milestone receivable from Pfizer 0 (100,000)
Prepaid expenses and other current assets 3,748 (3,916)
Amount due from related party 122 0
Other assets 392 112
Accounts payable (2,698) (8,676)
Accrued expenses and other current liabilities (2,906) (1,674)
Deferred revenue (25,141) 70,491
Amounts due to Pfizer 6,681 9,071
Cost share advance from Pfizer (25,831) (18,285)
Operating lease liabilities (502) (425)
Amounts due to related parties (11) (504)
Other liabilities 6 (1,699)
Net cash used in operating activities (76,005) (113,177)
Cash flows from investing activities:    
Purchases of marketable securities (10,171) (78,426)
Maturities of marketable securities 4,500 4,035
Purchases of property and equipment (72) 0
Net cash used in investing activities (5,743) (74,391)
Cash flows from financing activities:    
Proceeds from stock option exercises 1,191 4,135
Net cash provided by financing activities 1,191 4,135
Net change in cash, cash equivalents and restricted cash (80,557) (183,433)
Cash, cash equivalents and restricted cash, beginning of period 416,804 677,480
Cash, cash equivalents and restricted cash, end of period 336,247 494,047
Supplemental Disclosures of Non-Cash Financing Information:    
Change in fair value of share-based awards recorded to additional paid-in capital 0 1,377
Reclassification of share-based compensation liabilities to additional paid-in capital upon settlement of awards 0 1,862
Stock options exercised receivable, included in prepaid expenses and other current assets $ 0 $ 117