Financing Arrangements - Narrative (Details) - USD ($)			1 Months Ended		12 Months Ended
	Dec. 31, 2019	Dec. 30, 2019	Dec. 31, 2018	Oct. 31, 2017	Mar. 31, 2020	Mar. 31, 2019	Mar. 31, 2018	Dec. 27, 2019
Debt Instrument [Line Items]
Equity options, purchase price as a percentage of share price				105.00%
Equity commitment, number of consecutive trading days used for measuring share price				5 days
Equity option				$ 20,000,000.0
Debt issued					$ 113,700,000	$ 0	$ 0
Loss on extinguishment of debt					$ 4,851,000	$ 0	0
Common Shares
Debt Instrument [Line Items]
Warrants exercisable as a percentage of principal amount of loan				3.00%
Warrants outstanding (in USD per share)					73,710	73,710
Line of Credit | NovaQuest
Debt Instrument [Line Items]
Maximum borrowing commitment				$ 60,000,000.0
Debt issued			$ 54,000,000.0	6,000,000.0
Equity commitment related to note issuance				$ 20,000,000.0
Interest rate				15.00%
Quarterly interest rate				5.00%
Deferred interest rate				10.00%
Default interest rate				5.00%
Principal repayment of debt	$ 60,000,000.0
Accrued interest repayment of debt	7,600,000
Prepayment penalty	2,400,000
Term Loan | Hercules
Debt Instrument [Line Items]
Maximum borrowing commitment				$ 40,000,000.0
Interest rate				8.25%
Principal amount funded				$ 25,000,000.0			$ 15,000,000.0
End of term charge				6.55%
Principal repayment of debt	40,000,000.0
Accrued interest repayment of debt	300,000
Prepayment penalty	400,000
End-of-term charge	$ 2,600,000
Term Loan | Hercules | Prime Rate
Debt Instrument [Line Items]
Variable interest rate				4.00%
Tranche 1 | Common Shares
Debt Instrument [Line Items]
Number of securities exercisable by warrant (in shares)				49,800
Exercise price of warrants (in USD per share)				$ 15.06
Tranche 2 | Common Shares
Debt Instrument [Line Items]
Number of securities exercisable by warrant (in shares)							23,910
Exercise price of warrants (in USD per share)							$ 18.82
NovaQuest | Private Placement
Debt Instrument [Line Items]
Shares purchased by NovaQuest (in shares)				138,361
Shares purchased by NovaQuest				$ 2,000,000.0
NovaQuest | Private Placement, One
Debt Instrument [Line Items]
Shares purchased by NovaQuest (in shares)			1,082,977
Shares purchased by NovaQuest			$ 18,000,000.0
NovaQuest | Private Placement, Two
Debt Instrument [Line Items]
Shares purchased by NovaQuest (in shares)			1,203,307
Shares purchased by NovaQuest			$ 20,000,000.0
Majority Shareholder | Sumitomo Dainippon Pharma, Co., Ltd. | Term Loan | Letter Agreement with Sumitomo Dainippon Pharma, Co., Ltd.
Debt Instrument [Line Items]
Default interest rate								5.00%
Debt issued		$ 113,700,000