Subsequent Events (Details) - Subsequent Event - USD ($)	1 Months Ended
Oct. 31, 2017	Oct. 16, 2017
Subsequent Event [Line Items]
Equity option	$ 20,000,000
Equity option to be exercised in the current year	$ 10,000,000
Equity options, purchase price as a percentage of share price	105.00%
Equity commitment, number of consecutive trading days used for measuring share price	5 days
Common Shares
Subsequent Event [Line Items]
Warrants exercisable as a percentage of principal amount of loan	3.00%
Number of securities exercisable by warrant (in shares)	49,800
Exercise price of warrants (in USD per share)	$ 15.06
NovaQuest Securities Purchase Agreement \| Line of Credit
Subsequent Event [Line Items]
Maximum borrowing commitment	$ 60,000,000
Minimum borrowing commitment	$ 30,000,000
Interest rate	15.00%
Quarterly interest rate	5.00%
Deferred interest rate	10.00%
Equity commitment related to note issuance	$ 20,000,000
Equity commitment related to note issuance, portion of note issuance amount	0.3333
Hercules Loan Agreement \| Term Loan
Subsequent Event [Line Items]
Maximum borrowing commitment	$ 40,000,000
Interest rate	8.25%
Remaining borrowing commitment	$ 15,000,000
Principal amount funded		$ 25,000,000
Hercules Loan Agreement \| Term Loan \| Prime Rate
Subsequent Event [Line Items]
Variable interest rate	4.00%

Class of Warrant or Right, Maximum Percentage of Principal of Debt Instrument Allowed to be Exercisable

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- Definition

Debt Instrument, Equity Commitment

+ References

No definition available.

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- Definition

Debt Instrument, Equity Commitment, Percentage of Debt Outstanding

+ References

No definition available.

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- Definition

Debt Instrument, Interest Rate, Stated Deferred Rate

+ References

No definition available.

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- Definition

Debt Instrument, Interest Rate, Stated Quarterly Rate

+ References

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- Definition

Equity Commitment, Number of Consecutive Trading Days Used to Measure Price

+ References

No definition available.

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- Definition

Line of Credit Facility, Minimum Required Borrowings

+ References

No definition available.

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- Definition

Option Indexed to Issuer's Equity, Minimum Nominal Value Expected to Exercised in Current Year

+ References

No definition available.

+ Details

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- Definition

Option Indexed to Issuer's Equity, Nominal Value

+ References

No definition available.

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- Definition

Option Indexed to Issuer's Equity, Price as a Percentage of Share Price

+ References

No definition available.

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- Definition

Exercise price per share or per unit of warrants or rights outstanding.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(i)(4))
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690

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- Definition

Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(i)(2))
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690

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- Definition

Percentage points added to the reference rate to compute the variable rate on the debt instrument.

+ References

No definition available.

+ Details

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- Definition

Face (par) amount of debt instrument at time of issuance.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 55
-Paragraph 8
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- Definition

Contractual interest rate for funds borrowed, under the debt agreement.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22(a)(1))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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- Definition

Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.19(b),22(b))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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- Definition

Amount of borrowing capacity currently available under the credit facility (current borrowing capacity less the amount of borrowings outstanding).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.19(b),22(b))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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- Definition

Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event.

+ References

No definition available.

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