STATEMENTS OF CASH FLOWS (UNAUDITED) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows used in operating activities:
Net loss	$ (56,839)	$ (48,165)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	625	359
Noncash lease expense	842	572
Stock-based compensation	12,857	8,123
Amortization of premium and discount on marketable securities, net	1,784
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	1,557	1,044
Accounts payable	(838)	3,327
Accrued expenses and other liabilities	495	(856)
Operating lease liabilities	(846)	(459)
Net cash used in operating activities	(40,363)	(36,055)
Cash flows provided by (used in) investing activities:
Purchases of marketable securities	(27,140)
Proceeds from maturities of marketable securities	87,579
Purchases of property and equipment	(1,710)	(1,367)
Net cash provided by (used in) investing activities	58,729	(1,367)
Cash flows provided by financing activities:
Proceeds from the sale of common stock, net of offering costs		161,424
Proceeds from the issuance of common stock under ESPP	300
Proceeds from the issuance of common stock in connection with the exercise of stock options	212	808
Net cash provided by financing activities	512	162,232
Net increase in cash and cash equivalents	18,878	124,810
Cash, cash equivalents, and restricted cash at beginning of period	35,872	218,309
Cash, cash equivalents, and restricted cash at end of period	54,750	343,119
Supplemental disclosures:
Operating lease right-of-use assets obtained in exchange for operating lease liabilities	928
Property and equipment in accounts payable	77	$ 386
Unrealized loss on marketable securities	$ (1,583)