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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows used in operating activities:    
Net loss $ (111,694) $ (56,929)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 915 542
Noncash lease expense 1,328  
Loss on disposal of property and equipment   11
Stock-based compensation 20,931 5,583
Amortization of premium and discount on marketable securities, net 1,364  
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (1,382) (1,155)
Accounts payable 3,903 1,157
Accrued expenses and other liabilities 2,463 4,614
Operating lease liabilities (1,359)  
Net cash used in operating activities (83,531) (46,177)
Cash flows used in investing activities:    
Purchases of marketable securities (261,480)  
Purchases of property and equipment (2,323) (621)
Net cash used in investing activities (263,803) (621)
Cash flows provided by financing activities:    
Proceeds from the sale of common stock, net of offering costs 161,424  
Proceeds from the issuance of common stock upon initial public offering, net of offering costs   166,630
Payment of offering costs (303) (12)
Payment of capital lease obligation   (258)
Proceeds from issuance of common stock in connection with the exercise of stock options 3,504 100
Proceeds from the issuance of common stock under ESPP 272  
Net cash provided by financing activities 164,897 246,228
Net (decrease) increase in cash and cash equivalents (182,437) 199,430
Cash, cash equivalents and restricted cash at beginning of year 218,309 18,879
Cash, cash equivalents and restricted cash at end of year 35,872 218,309
Supplemental disclosures:    
Operating lease right-of-use assets obtained in exchange for operating lease liabilities 567  
Property and equipment in accounts payable 806 765
Unrealized gain (loss) on marketable securities $ (711)  
Offering costs in accrued expenses   265
Offering costs in accounts payable   24
Series C Convertible Preferred Stock    
Cash flows provided by financing activities:    
Proceeds from the sale of convertible preferred stock, net of offering costs   49,826
Series B Convertible Preferred Stock    
Cash flows provided by financing activities:    
Proceeds from the sale of convertible preferred stock, net of offering costs   $ 29,942