X0407 4 2023-05-23 false 0001678660 Prelude Therapeutics Inc PRLD 0001329010 Chardonnet Laurent C/O PRELUDE THERAPEUTICS INCORPORATED 200 POWDER MILL ROAD WILMINGTON DE 19801 false true false false Chief Financial Officer false Common Stock 2023-05-23 4 P false 5000.00 5.50 A 42165.00 D The reported total includes 1,292 shares of common stock the reporting person has acquired since the date of his last ownership report through the issuer's Employee Stock Purchase Plan in one or more transactions exempt pursuant to Rules 16b-3(c). /s/ Bryant D. Lim, as Attorney-in-Fact 2023-05-25