X0607 3 2026-04-15 1 0001678660 Prelude Therapeutics Inc PRLD 0001489966 Morris Charles Q false C/O PRELUDE THERAPEUTICS INCORPORATED 175 INNOVATION BOULEVARD WILMINGTON DE 19805 true Chief Medical Officer Exhibit 24 - Power of Attorney /s/ Bryant D. Lim, Attorney-in-Fact 2026-04-15