0001678660 2025-11-03 2025-11-03 false 0001678660 false 8-K 2025-11-03 Prelude Therapeutics Incorporated DE 001-39527 81-1384762 175 Innovation Boulevard Wilminton DE 19805 302 467-1280 false false false false Common Stock, $0.0001 par value per share PRLD NASDAQ true