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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Cash flows from operating activities:      
Net loss $ (57,474,000) $ (96,388,000) $ (12,545,000)
Adjustments to reconcile net loss to cash used in operating activities:      
Depreciation expenses 48,000 32,000 18,000
Share-based compensation 6,560,000 22,683,000
Research and development expense, patent cost 42,259,000
Other income from government grant (307,000)
Changes in assets and liabilities:      
Advances to suppliers 316,000 (726,000) (710,000)
Due from related parties (481,000)
Prepaid expenses and other current assets (28,000) 96,000 (334,000)
Other noncurrent assets (549,000) (240,000) (121,000)
Accounts payable 6,207,000 2,935,000 144,000
Due to related parties (210,000) (222,000)
Accrued expenses 4,688,000 699,000 (102,000)
Other current liabilities 1,065,000 64,000 174,000
Net cash used in operating activities (39,955,000) (28,796,000) (13,698,000)
Cash flows from investing activities:      
Acquisitions of property and equipment (207,000) (76,000) (64,000)
Purchase of short-term investments (3,074,000)
Proceeds from maturity of short-term investments 3,074,000
Net cash (used in) provided by investing activities 2,867,000 (3,150,000) (64,000)
Cash flows from financing activities:      
Proceeds from issuance of ordinary shares 14,000,000 50,505,000 15,250,000
Net cash provided by financing activities 13,245,000 47,722,000 14,713,000
Effect of foreign exchange rate changes 251,000 18,000 (85,000)
Net increase (decrease) in cash and cash equivalents (23,592,000) 15,794,000 866,000
Cash at beginning of year 27,481,000 11,687,000 10,821,000
Cash at end of year 3,889,000 27,481,000 11,687,000
Non-cash activities:      
Initial public offering costs accrued in accrued expenses 1,324,000
Research and development expense, patent cost 42,259,000
IPO [Member]      
Cash flows from financing activities:      
Payments of shares offering costs $ (755,000) $ (2,783,000) $ (537,000)