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Note 3 - Property and Equipment, Net (Tables)
 12 Months Ended
Dec. 31, 2018
Notes Tables  
Property, Plant and Equipment [Table Text Block]
    December 31,  
    2017     2018  
Office equipment    
39
      
143
  
Laboratory equipment    
104
      
111
  
Motor vehicles    
23
      
23
  
Leasehold improvements    
13
      
109
  
     
179
      
386
  
Less: accumulated depreciation    
(56
 )    
(104
 )
Property and equipment, net    
123
      
282