August 26, 2019

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

100 F Street N.E.

Washington, D.C. 20549-3720

Attention: Stacie Gorman

Re: Innovative Industrial Properties, Inc.
Registration Statement on Form S-3 (File No. 333-233311)
REQUEST FOR ACCELERATION OF EFFECTIVENESS

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Innovative Industrial Properties, Inc. (the “Company”) hereby requests that the above-referenced Registration Statement on Form S-3 (File. No. 333-233311) (the “Registration Statement”) be declared effective on August 28, 2019, or as soon as practicable thereafter.

Sincerely,

INNOVATIVE INDUSTRIAL PROPERTIES, INC.

By: /s/ Brian Wolfe                                                        

Name:  Brian Wolfe

Title:  Vice President, General Counsel, and Secretary