Revenue Recognition - Contract Balance - Additional Information (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Contract liabilities	$ 60,232	$ 83,773
GSK Collaboration Agreement
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Accounts receivable	1,100	1,900
Contract liabilities	$ 60,200	$ 83,800