Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Income Tax Disclosure [Abstract]

Schedule of Provision for Income Taxes

The provision for income taxes differs from the amount expected by applying the federal statutory rate to the loss before taxes as follows:

	Year Ended December 31,
	2021			2020			2019
Federal statutory income tax rate		21.0	%		21.0	%		21.0	%
State income taxes		0.7	%		(1.9	%)		7.0	%
Change in valuation allowance		(25.2	%)		(21.5	%)		(31.4	%)
Research tax credits		3.8	%		2.7	%		3.6	%
Other permanent differences		(0.3	%)		(0.3	%)		(0.4	%)
Change in fair value of redeemable convertible preferred stock liability		0.0	%		0.0	%		0.2	%
Provision for income taxes		0.0	%		0.0	%		0.0	%

Schedule of Tax Effects of Temporary Differences and Carryforwards of Deferred Tax Assets

The tax effects of temporary differences and carryforwards of the deferred tax assets are presented below (in thousands):

	As of December 31,
	2021			2020
Deferred tax assets:
Net operating loss carryforwards	$	27,324		$	13,418
Research and development credit carryforwards		5,939			3,813
Lease liability		1,097			1,420
Intangible assets		1,179			1,274
Stock-based compensation		1,725			705
Accruals and reserves		882			505
Deferred revenue		12,575			17,332
Gross deferred tax assets		50,721			38,467
Less: Valuation allowance		(49,575	)		(36,879	)
Deferred tax assets, net of valuation allowance		1,146			1,588
Deferred tax liabilities:
Right-of-use assets		(825	)		(1,100	)
Property and equipment		(321	)		(488	)
Net deferred tax assets	$	—		$	—

Summary of Activity Related to Company?s Unrecognized Tax Benefits

The following table summarizes the activity related to the Company’s unrecognized tax benefits (in thousands).

Balance as of January 1, 2020	$	746
Increase related to prior year tax positions		2
Increase related to current year tax positions		153
Balance as of December 31, 2020	$	901
Increase related to prior year tax positions		73
Increase related to current year tax positions		330
Balance as of December 31, 2021	$	1,304