Condensed Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Cash flows from operating activities
Net loss	$ (149,669)	$ (92,344)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation and amortization	1,318	1,238
Net accretion of discounts on marketable securities	(6,470)	(12,954)
Stock-based compensation	22,105	16,046
Amortization of right-of-use assets	1,048	941
Changes in assets and liabilities
Prepaid expenses and other assets	(2,470)	(3,487)
Accounts payable	2,364	9,243
Accrued and other liabilities	7,718	5,625
Lease liabilities	1,240	(1,003)
Net cash used in operating activities	(122,816)	(76,695)
Cash flows from investing activities
Purchases of property and equipment, net	(1,993)	(2,298)
Purchases of marketable securities	(232,760)	(640,544)
Maturities of marketable securities	360,488	357,428
Net cash provided by (used in) investing activities	125,735	(285,414)
Cash flows from financing activities
Proceeds from issuance of common stock related to at-the-market offering program, net of issuance costs	24,984	379,971
Proceeds from ESPP purchase	820	781
Proceeds from exercise of common stock options	1,544	7,542
Net cash provided by financing activities	27,348	388,294
Net increase in cash, cash equivalents and restricted cash	30,267	26,185
Cash, cash equivalents and restricted cash, at beginning of period	85,183	157,775
Cash, cash equivalents and restricted cash, at end of period	115,450	183,960
Reconciliation of cash, cash equivalents and restricted cash
Cash and cash equivalents	114,645	183,049
Restricted cash	805	911
Cash, cash equivalents and restricted cash	115,450	183,960
Supplemental disclosure of cash flow information:
Cash paid for interest		22
Supplemental non-cash investing and financing activities:
Right-of-use asset obtained in exchange for a new operating lease liability	6,186
Purchases of property and equipment in accounts payable and accrued liabilities	$ 657	45
Unpaid at-the-market offering program costs		$ 16