The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abeona Therapeutics, Inc. Common 00289Y206   11,646,186 1,842,751 SH   SOLE   1,842,751 0 0
Adverum Biotechnologies, Inc. Common 00773U207   5,849,998 833,333 SH   SOLE   833,333 0 0
Aligos Therapeutics Inc Common 01626L204   1,228,672 141,879 SH   SOLE   141,879 0 0
Allakos Inc Common 01671P100   1,930,931 2,956,110 SH   SOLE   2,956,110 0 0
ALX Oncology Holdings Inc Common 00166B105   7,342,830 4,034,522 SH   SOLE   4,034,522 0 0
Astria Therapeutics Inc Common 04635X102   17,095,062 1,552,685 SH   SOLE   1,552,685 0 0
Avadel Pharmaceuticals PLC ADR G29687103   35,202,090 2,684,109 SH   SOLE   2,684,109 0 0
Bolt Therapeutics Inc Common 097702104   2,281,797 3,521,291 SH   SOLE   3,521,291 0 0
Celcuity Inc Common 15102K100   9,102,555 610,500 SH   SOLE   610,500 0 0
Codexis, Inc Common 192005106   1,195,484 388,144 SH   SOLE   388,144 0 0
Cogent Biosciences Inc Common 19240Q201   12,122,687 1,122,471 SH   SOLE   1,122,471 0 0
Compass Pathway PLC SPONSORED ADS 20451W101   10,130,400 1,608,000 SH   SOLE   1,608,000 0 0
Compass Therapeutics Inc Common 20454B104   6,543,082 3,556,023 SH   SOLE   3,556,023 0 0
Corbus Pharmaceuticals Holdings Common 21833P301   3,440,960 166,794 SH   SOLE   166,794 0 0
Corvus Pharmaceuticals Holdings Common 221015100   7,905,575 1,497,268 SH   SOLE   1,497,268 0 0
DBV Technologies SA SPONSORED ADS 23306J200   948,106 1,354,437 SH   SOLE   1,354,437 0 0
Delcath Systems, Inc. Common 24661P807   9,002,955 997,005 SH   SOLE   997,005 0 0
Dyne Therapeutics Inc Common 26818M108   40,049,363 1,114,960 SH   SOLE   1,114,960 0 0
Engene Holdings Inc. Common 29286M105   4,479,453 678,705 SH   SOLE   678,705 0 0
Erasca Inc Common 29479A108   18,445,944 6,756,756 SH   SOLE   6,756,756 0 0
Geron Corp Common 374163103   123,602,826 27,225,292 SH   SOLE   27,225,292 0 0
Harmony Biosciences Holdings Inc Common 413197104   104,249,880 2,606,247 SH   SOLE   2,606,247 0 0
Instil Bio Inc Common 45783C200   42,030,501 624,339 SH   SOLE   624,339 0 0
IO Biotech Inc Common 449778109   6,482,111 6,173,439 SH   SOLE   6,173,439 0 0
Olema Pharmaceuticals Inc Common 68062P106   17,979,992 1,505,862 SH   SOLE   1,505,862 0 0
Oric Pharmaceuticals Inc Common 68622P109   13,097,635 1,277,818 SH   SOLE   1,277,818 0 0
Precision Biosciences Inc Common 74019P207   41,888 4,675 SH   SOLE   4,675 0 0
Q32 Bio Inc. Common 746964105   917,343 20,559 SH   SOLE   20,559 0 0
Regulus Therapeutics Inc Common 75915K309   7,850,000 5,000,000 SH   SOLE   5,000,000 0 0
Rezolute Inc Common 76200L309   13,568,864 2,797,704 SH   SOLE   2,797,704 0 0
Sera Prognostics Inc Common 81749D107   12,873,432 1,650,440 SH   SOLE   1,650,440 0 0
Silence Therapeutics PLC ADS 82686Q101   20,097,154 1,105,454 SH   SOLE   1,105,454 0 0
Sinovac Biotech Ltd. SHS P8696W104   76,346,000 11,800,000 SH   SOLE   11,800,000 0 0
Soleno Therapeutics Inc Common 834203309   317,675,557 6,291,851 SH   SOLE   6,291,851 0 0
Tenax Therapeutics Inc Common 88032L605   720,832 208,333 SH   SOLE   208,333 0 0
Terns Pharmaceuticals Inc Common 880881107   57,510,522 6,895,746 SH   SOLE   6,895,746 0 0
Tourmaline Bio Inc. Common 89157D105   15,217,286 591,882 SH   SOLE   591,882 0 0
Trevi Therapeutics Inc Common 89532M101   5,387,096 1,612,903 SH   SOLE   1,612,903 0 0
Unicycive Therapeutics Common 90466Y103   1,823,375 4,470,152 SH   SOLE   4,470,152 0 0
Verastem Inc Common 92337C203   4,599,998 1,538,461 SH   SOLE   1,538,461 0 0
Verona Pharma PLC SPONSORED ADS 925050106   102,126,538 3,549,758 SH   SOLE   3,549,758 0 0
Viridian Therapeutics Inc Common 92790C104   38,179,209 1,678,207 SH   SOLE   1,678,207 0 0
Zenas Biopharma Inc Common 98937L105   20,020,759 1,183,260 SH   SOLE   1,183,260 0 0