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Income Taxes - Schedule of Reconciliation of Income Tax Expense Computed at Statutory Corporate Income Tax Rate to Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Reconciliation of Effective Income Tax Rate      
Income tax expense at statutory rate 9.30% 9.30% 9.30%
State income tax, net of federal benefit (2.10%) 0.70% 0.30%
Nondeductible expenses (0.10%) 0.00% 0.00%
Foreign rate differential 2.00% (0.40%) (2.50%)
Statutory to US GAAP permanent differences 0.10% 1.00% 1.80%
Stock-based compensation (2.00%) 1.40% (2.90%)
Impact of deferred rate change (12.20%) 0.00% 0.00%
Research credits (5.20%) 1.80% 0.80%
Change in valuation allowance 10.90% (14.10%) (9.40%)
Effective income tax rate 0.70% (0.30%) (2.60%)