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Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Total
ViaCyte [Member]
Common Shares [Member]
Common Shares [Member]
ViaCyte [Member]
Treasury Shares [Member]
Treasury Shares [Member]
ViaCyte [Member]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
ViaCyte [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Beginning balance at Dec. 31, 2017 $ 187,832   $ 1,240       $ 312,018   $ (125,440) $ 14
Beginning balance (in shares) at Dec. 31, 2017     40,592,248   444,873          
Cumulative effect of ASC 606 adoption | ASU 2014-09 [Member] (1,148)               (1,148)  
Issuance of common shares, net of issuance costs 122,597   $ 174       122,423      
Issuance of common shares, net of issuance costs (in shares)     5,750,000              
Vesting of restricted shares 13           13      
Vesting of restricted shares (in shares)     10,042              
Exercise of vested options 2,656   $ 9       2,647      
Exercise of vested options (in shares)     328,525   (6,253)          
Stock-based compensation expense 6,673           6,673      
Other comprehensive loss 12                 12
Net loss (28,300)               (28,300)  
Ending balance at Mar. 31, 2018 290,335   $ 1,423       443,774   (154,888) 26
Ending balance (in shares) at Mar. 31, 2018     46,680,815   438,620          
Beginning balance at Dec. 31, 2017 187,832   $ 1,240       312,018   (125,440) 14
Beginning balance (in shares) at Dec. 31, 2017     40,592,248   444,873          
Net loss (117,391)                  
Ending balance at Sep. 30, 2018 417,314   $ 1,575   $ (57)   659,776   (243,979) (1)
Ending balance (in shares) at Sep. 30, 2018     51,554,479   307,936          
Beginning balance at Mar. 31, 2018 290,335   $ 1,423       443,774   (154,888) 26
Beginning balance (in shares) at Mar. 31, 2018     46,680,815   438,620          
Vesting of restricted shares 14   $ 1       13      
Vesting of restricted shares (in shares)     10,043              
Exercise of vested options 3,729   $ 11   $ (50)   3,768      
Exercise of vested options (in shares)     380,977   (29,259)          
Stock-based compensation expense 9,477           9,477      
Other comprehensive loss (21)                 (21)
Net loss (38,380)               (38,380)  
Ending balance at Jun. 30, 2018 265,154   $ 1,435   $ (50)   457,032   (193,268) 5
Ending balance (in shares) at Jun. 30, 2018     47,071,835   409,361          
Issuance of common shares, net of issuance costs 184,456   $ 137       184,319      
Issuance of common shares, net of issuance costs (in shares)     4,210,526              
Vesting of restricted shares 21   $ 1       20      
Vesting of restricted shares (in shares)     10,046              
Exercise of vested options 1,841   $ 2       1,839      
Exercise of vested options (in shares)     161,388   (741)          
Repurchase of treasury shares (7)       $ (7)          
Repurchase of treasury shares (in shares)     (64,952)   64,952          
Issuance of treasury shares to ViaCyte   $ 7,500           $ 7,500    
Issuance of treasury shares to ViaCyte (in shares)       165,636   (165,636)        
Stock-based compensation expense 9,066           9,066      
Other comprehensive loss (6)                 (6)
Net loss (50,711)               (50,711)  
Ending balance at Sep. 30, 2018 417,314   $ 1,575   $ (57)   659,776   (243,979) (1)
Ending balance (in shares) at Sep. 30, 2018     51,554,479   307,936          
Beginning balance at Dec. 31, 2018 392,195   $ 1,584   $ (57)   682,245   (291,569) (8)
Beginning balance (in shares) at Dec. 31, 2018     51,852,862   307,936          
Issuance of common shares, net of issuance costs 23,472           23,472      
Issuance of common shares, net of issuance costs (in shares)     631,580              
Vesting of restricted shares 15           15      
Vesting of restricted shares (in shares)     9,288              
Exercise of vested options 1,832   $ 5       1,827      
Exercise of vested options (in shares)     141,915              
Stock-based compensation expense 10,696           10,696      
Other comprehensive loss 8                 8
Net loss (48,408)               (48,408)  
Ending balance at Mar. 31, 2019 379,810   $ 1,589   $ (57)   718,255   (339,977)  
Ending balance (in shares) at Mar. 31, 2019     52,635,645   307,936          
Beginning balance at Dec. 31, 2018 $ 392,195   $ 1,584   $ (57)   682,245   (291,569) (8)
Beginning balance (in shares) at Dec. 31, 2018     51,852,862   307,936          
Exercise of vested options (in shares) 475,062                  
Net loss $ 36,316                  
Ending balance at Sep. 30, 2019 591,878   $ 1,684   $ (57)   845,526   (255,253) (22)
Ending balance (in shares) at Sep. 30, 2019     55,189,370   256,989          
Beginning balance at Mar. 31, 2019 379,810   $ 1,589   $ (57)   718,255   (339,977)  
Beginning balance (in shares) at Mar. 31, 2019     52,635,645   307,936          
Issuance of common shares, net of issuance costs 28,114   $ 40       28,074      
Issuance of common shares, net of issuance costs (in shares)     732,108   (47,297)          
Vesting of restricted shares 16   $ 1       15      
Vesting of restricted shares (in shares)     12,317              
Exercise of vested options 1,254           1,254      
Exercise of vested options (in shares)     118,987   (3,650)          
Stock-based compensation expense 12,198           12,198      
Other comprehensive loss (10)                 (10)
Net loss (53,699)               (53,699)  
Ending balance at Jun. 30, 2019 367,683   $ 1,630   $ (57)   759,796   (393,676) (10)
Ending balance (in shares) at Jun. 30, 2019     53,499,057   256,989          
Issuance of common shares, net of issuance costs 68,661   $ 43       68,618      
Issuance of common shares, net of issuance costs (in shares)     1,452,880              
Vesting of restricted shares 12   $ 1       11      
Vesting of restricted shares (in shares)     34,328              
Exercise of vested options 2,338   $ 10       2,328      
Exercise of vested options (in shares)     203,105              
Stock-based compensation expense 14,773           14,773      
Other comprehensive loss (12)                 (12)
Net loss 138,423               138,423  
Ending balance at Sep. 30, 2019 $ 591,878   $ 1,684   $ (57)   $ 845,526   $ (255,253) $ (22)
Ending balance (in shares) at Sep. 30, 2019     55,189,370   256,989