Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 437,549	$ 456,649
Accounts receivable, including related party amounts of $331 and $88 as of March 31, 2019 and December 31, 2018, respectively	331	88
Prepaid expenses and other current assets, including related party amounts of $4,775 and $3,417 as of March 31, 2019 and December 31, 2018, respectively	11,916	9,658
Total current assets	449,796	466,395
Property and equipment, net	18,871	18,500
Intangible assets, net	276	289
Restricted cash	3,163	3,163
Operating lease assets	25,098
Other non-current assets	669	669
Total assets	497,873	489,016
Current liabilities:
Accounts payable	7,131	5,069
Accrued expenses, including related party amounts of $2,483 and $1,700 as of March 31, 2019 and December 31, 2018, respectively	15,680	20,852
Accrued tax liabilities	615	402
Deferred rent		1,202
Operating lease liabilities	4,899
Other current liabilities	73	221
Total current liabilities	28,398	27,746
Deferred revenue non-current, including related party amounts of $57,755 and $57,780 as of March 31, 2019 and December 31, 2018, respectively	57,755	57,780
Deferred rent non-current		11,052
Operating lease liabilities, net of current portion	31,728
Other non-current liabilities	182	243
Total liabilities	118,063	96,821
Commitments and contingencies, see Note 5
Shareholders’ equity:
Common shares, CHF 0.03 par value, 53,325,963 and 52,183,139 shares authorized at March 31, 2019 and December 31, 2018, respectively, 52,943,581 and 52,160,798 shares issued at March 31, 2019 and December 31, 2018, respectively, 52,635,645 and 51,852,862 shares outstanding at March 31, 2019 and December 31, 2018, respectively, 20,498,996 shares in conditional capital at March 31, 2019 and December 31, 2018.	1,589	1,584
Treasury shares, at cost, 307,936 shares at March 31, 2019 and December 31, 2018	(57)	(57)
Additional paid-in capital	718,255	682,245
Accumulated deficit	(339,977)	(291,569)
Accumulated other comprehensive loss		(8)
Total shareholders' equity	379,810	392,195
Total liabilities and shareholders’ equity	$ 497,873	$ 489,016