Segment Information - Schedule of Reportable Segment Profit and Loss, Including Significant Expense Categories, Attributable to the Company's Reportable Segment (Details) (Parenthetical) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Segment Reporting Information [Line Items]
Stock-based compensation expense	$ 86,567	$ 81,028	$ 97,947
Depreciation	19,200	19,800	24,100
Interest income on investments	104,300	76,400	23,300
Research and Development Expense [Member]
Segment Reporting Information [Line Items]
Stock-based compensation expense	47,944	46,356	53,956
Depreciation	10,300	10,900	10,600
Non-cash adjustment	4,800
General and Administrative Expense [Member]
Segment Reporting Information [Line Items]
Stock-based compensation expense	38,623	34,672	43,991
Depreciation	$ 8,900	$ 8,900	$ 13,500